The health care industry in the United States is being reshaped by a dramatic shift away from acute care and towards chronic care (called the A2C shift). By 2020, it is expected that half of the US population will suffer from chronic disease and that the management of these conditions will represent 80% of health care spending. These changes will have a profound effect on demand and associated supply chains. For example, a surge in demand for home-based health care services is expected. The MIT Efficient Healthcare Delivery Project (MEHD) is a multi-year research effort, created by the MIT Center for Transportation & Logistics, to identify and analyze structural changes in the health care industry. The project is developing ways to build the supply chains that will support the new generation of A2C health care services.